Isaiah Washington will not return to Grey's Anatomy following his use of a gay slur.
According to ABC Television Studios, producer of the award-winning medical drama, his contract option has not been renewed for next season.
"I'm mad as hell and I'm not going to take it anymore," Washington said in a statement released by his publicist.
The actor, who plays Dr Preston Burke in the show, did not explain his words - a quote from the 1976 film Network.
Washington, 43, was involved in a scuffle with co-star Patrick Dempsey on the set of Grey's Anatomy last year after using the word "fa***t" about co-star, T R Knight.